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A Retrospective Survey of Presentation Features of Breast Cancer and Risk Factors for Treatment Outcome

Institutions in Peru (Instituto Nacional des Enfermedades Neoplasicas), Egypt (NCI, Cairo), India (Cancer Institute, Chennai) and Pakistan (Jinnah Hospital) contributed data for 8880 women with breast cancer treated between 1993 and 2001. Partial support for this study was obtained from the Komen for the Cure Foundation and from the then Office of International Affairs, NCI. The major findings showed that women with lower socioeconomic status and less education presented with more advanced disease.   

The Treatment and Characterization of Acute Lymphoblastic Leukemia in Children, Adolescents and Young Adults

This study was conducted by four institutions in India – the All India Institute of Medical Sciences, New Delhi, the Cancer Institute, Chennai, the Tata Memorial Center, Mumbai and the Jaslok Hospital and Research Centre in Mumbai.  Patient enrollment began in 2004 and was completed in August, 2009.  A total of 473 patients were entered onto the study.  Partial support for this study was obtained from the Sir Ratan Tata Trust. The major results of this study showed an improved overall survival than that achieved with the predecessor protocol, MCP841.  

A Descriptive Study of Nasopharyngeal Carcinoma (NPC) in Low and Middle Income Countries

Institutions in Brazil, Turkey, Pakistan, India and Malaysia participated in a questionnaire study of adult patients and parents of children with NPC in order to learn more about the factors that may contribute to delays in diagnosis and treatment, to assess consanguinity and family history of NPC, and to collect clinical features at the time of presentation.  More than 100 questionnaires were collected.